The use of respiratory devices (IMT and / or oscillatory PEP) have been shown to:

  • Produce beneficial effects in terms of increased respiratory fitness in healthy humans and in patients with cystic fibrosis, COPD, asthma, and neurological weakness
  • Reduce breathlessness in healthy humans and patients with asthma and COPD
  • Improve sputum clearance in patients with cystic fibrosis and bronchiectasis
  • Improve quality of life in patients with COPD, bronchiectasis and neurological weakness

Evidence for inspiratory muscle training and oscillatory positive expiratory pressure

AEROSURE’s mode of action is based on two well-established systems that have been used in various settings for many years in people with respiratory diseases; these are Inspiratory Muscle Training (IMT) effects and Oscillatory Positive Expiratory Pressure (OPEP). IMT and OPEP are included in the physiotherapy guidelines and the National Institute for Health and Care Excellence in the United Kingdom COPD guidelines.

Inspiratory Muscle Training:

IMT is a technique designed to directly affect the functioning of respiratory muscles which are responsive to training. IMT can benefit people with COPD and other conditions involving inspiratory muscle weakness. IMT has demonstrated a number of benefits in a wide range of studies, both in healthy subjects and in people with clinical conditions. Often reported benefits are:

  • Increased inspiratory muscle strength
  • Reduced dyspnoea (shortness of breath)
  • Increased exercise performance
  • Improved quality of life

Oscillatory Positive Expiratory Pressure: summary

OPEP devices are designed to interrupt the expiratory airflow, which results in the airways vibrating and so loosening mucus. Furthermore, vibration stimulations applied to the inspiratory system:

  • Reduce shortness of breath in healthy humans at rest
  • Reduce shortness of breath during exercise in people with COPD

The primary benefits of OPEP are:

  • Decrease in mucus and phlegm viscoelasticity
  • Increase in forces disconnecting mucus and phlegm from the air passages
  • Increase in mucus and phlegm expectoration (Coughing up)

OPEP devices have been routinely used as part of pulmonary rehabilitation programmes for a range of conditions, eg, CF, COPD, and bronchiectasis.

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